Malanin D.A., Zhulikov A.L., Novochadov V.V. Morphology of regeneration in experimental non-full-thickness defects of hyaline cartilage after their cold ablation

Malanin Dmitry Aleksandrovich
Doctor of Medical Sciences, Professor, Head of Department of Traumatology and Orthopedics and Field Military Surgery, Volgograd State Medical University
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Zhulikov Aleksander Leonidovich
Candidate of Medical Sciences, Associate Professor, Department of Traumatology and Orthopedics and Field Military Surgery, Volgograd State Medical
University
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Novochadov Valery Valeryevich
Doctor of Medical Sciences, Professor, Head of Department of Bioengineering and Bioinformatics, Volgograd State University

Summary: The article armed to analyze morphologically the regenerates placed on the experimental nonfullthickness defects of hyaline cartilage in canine knee. The results of spontaneous regeneration, mechanical debridement, and cold ablation using radiofrequency device “Atlas” (“ArthroCare”, US) were monitored during 16 weeks after damage. The beneficial effect of cold ablation was revealed as more early and whole restoration of articular surface (smoothing), the increase of chondral tissue ratio in regenerates, as the decrease of vascularization and growth of connective tissue. Regarding the pathologic regeneration in chondrocyte claster formation to late terms of experience the effect of cold ablation was called in question.
Key words: articular cartilage, chondrocytes, regeneration, debridement, cold ablation.

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Morphology of regeneration in experimental non-full-thickness defects of hyaline cartilage after their cold ablation by Malanin D.A., Zhulikov A.L., Novochadov V.V. is licensed under a Creative Commons Attribution 4.0 International License.
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