Novochadov V.V., Malanin D.A., Gayfullin N.M., Suchilin I.A. Zonal organization of tissue regenerates after grafting of full-thickness chondral defects using hydroxyapatite – collagen scaffolds

Novochadov V.V.
Doctor of medical sciences, Professor, Head of Department of Bioengineering and Bioinformatics, Volgograd State University 
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Malanin D.A.
Doctor of medical sciences, Professor, Head of Department of Traumatology and Orthopedics and Field Military Surgery, Volgograd State Medical University
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Gayfullin N.M.
Candidate of medical sciences, Associate Professor, Department of Physiology and Pathology, Moscow State University named after M.V. Lomonosov
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Suchilin I.A.
Assistant, Department of Traumatology and Orthopedics and Field Military Surgery, Volgograd State Medical University
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Summary: The peculiarities of zonal structure formation in tissue regenerates after replacement of fullthickness chondral defects by hydroxyapatite – collagen scaffolds («Collapan») were revealed compareing to results of autogenic chondroplasty. The experiments were conducted using 38 knee joints of inbred dogs, and monitoring due to 4, 8, 16 and 24 weeks after grafting. More accurate restoration of articular surface has improved morphologically for the use of the tissue scaffolds like formation of mixed chondral tissue with the partial zonal organization by 16 week.
Key words: articular cartilage, chondroplasty, hydroxyapatite, collagen, bioengineering.
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Zonal organization of tissue regenerates after grafting of full-thickness chondral defects using hydroxyapatite – collagen scaffolds by Novochadov V.V., Malanin D.A., Gayfullin N.M., Suchilin I.A. is licensed under a Creative Commons Attribution 4.0 International License.
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