Abstract. The article is devoted to the study of the features of circadian dynamics of biochemical parameters of oral fluid of people with different individual-typological organization. The study involved a volunteer of both sexes aged from 18 to 20 years of full-time students of Volgograd state University. In order to assess the features of circadian metabolism in people with different chronotype, the oral fluid studied the content of four metabolites related to different types of metabolism: glucose, cholesterol and triglycerides, albumins. In the experimental research have identified circadian dynamics of biochemical parameters of oral fluid. Identified key combinations of chronotype, providing expressed by the dynamics of glucose, triglycerides albumin during the day. Thus, for a person in daylight hours characterized by a friendly monophase increase in glucose, triglycerides, cholesterol, albumins in the oral fluid with acrophase at 13.00 and an amplitude of oscillations from 19 % to 42 % around the mesor. The revealed connections as a result of correlation are additional proof that circadian dependence of the content of metabolites in the oral fluid significantly differs, and depends on the chronotype of the person. At the same time, the content of albumin is in this regard the most organized indicator, the use of which is quite possible for further study of the relationship between the functional system of the organism and the circadian organization of life, for example, under test loads.

Key words: functional status, circadian rhythms, biochemical parameters, chronotype, oral liquid.