Candidate of Medical Sciences, Associate Professor, Department of Orthopedic Dentistry, First Moscow Medical University

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Trubetskaya St., 8/2, 119991 Moscow, Russian Federation

Abstract. The study deals with comparison of physico-chemical (pH, buffer capacity, viscosity) and biochemical (concentration of albumin, calcium, phosphate, the activity of aamylase and alkaline phosphatase) variables in the mixed saliva (oral fluid, OF) in persons with dental implants depending on its number (1-2 or 3 and more) and time after installation (2-4 and 5-11 months), and those with satisfactory state of oral health and without implants. The pH value in OF was almost similar in patients of group comparison and at different times after implantation and at different number of implants. The OF buffer capacity in different periods after the installation of single implants varied, been typical for the comparison group. A 2.4-fold decrease of buffer capacity was character at 2-4 months after installation of three or more implants, later this decline has not recovered fully. The installation of a single implant was not accompanied by changes in the OF viscosity, while multiple dental implant installation let to increase of viscosity 2.1 times less than in the comparison group at 2-4 months terms. The alterations of some biochemical properties of OF after dental implantation were shown to depend on the number and timing since the load on the installed constructions. Thus, more significant changes in oral fluid are to reduce the buffer capacity and viscosity of oral fluid, the concentration of calcium ions and the activity of a-amylase, they may be stored at the time of 5-11 months after implantation. These changes are associated with possible functional properties of oral fluid, which may affect the adaptation of dental system to new functional conditions connected to dental implant installation.

Key words: dental implantation, saliva, oral fluid, buffer capacity, electrolytes, amylase, alkaline phosphatase.